Among his discoveries were cellists Yo-Yo Ma and Jian Wang (cellist), and violinists Itzhak Perlman and Pinchas Zukerman. He also played a major role in saving New York City's Carnegie Hall from demolition in 1960 which later had its main auditorium named in his honour. Among his many recordings, Stern recorded concertos by Johannes Brahms, Johann Sebastian Bach, Beethoven, Felix Mendelssohn and Antonio Vivaldi and modern works by Samuel Barber, Béla Bartók, Igor Stravinsky and Leonard Bernstein. He also dubbed actors' violin-playing in several films, one of which was Fiddler on the Roof. Stern's favorite violin was the Ysaye Guarneri del Gesù, one of the violins produced by the Cremonese luthier Giuseppe Guarneri del Gesù. He owned also a Vuillaume and two contemporary instruments by Samuel Zygmuntowicz. In his autobiography written with Chaim Potok, My First 79 Years, he cites Nathan Milstein and Arthur Grumiaux as major influences on his style of playing. In 1979, eight years after Nixon's first official visit, the People's Republic of China offered Stern and pianist David Golub an unprecedented invitation to tour the country. Their visit was filmed and resulted in an Oscar-winning documentary From Mao to Mozart. In 1987, Stern received the Grammy Award for Lifetime Achievement. His November 1948 marriage to ballerina Nora Kaye ended in divorce in 1949.
On August 17, 1951, Isaac married Vera Lindenblit. They had three children together. Their marriage ended in divorce in 1994 after 43 years of marriage. On January 23, 1997, Isaac married his third wife, Linda Reynolds, who survived him. Isaac Stern died on September 22, 2001 of congestive heart failure at 81.
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